I'm not sure about the technical aspects of it, but my TC only has one compartment behind the drive axles (about 48") and I've dragged the trailer hitch a couple times. I've often wondered how the rigs with even more overhang manage it.
2006 Renegade/Freightliner Coronado 43', Detroit, twin screw, 12spd
2001 Ford Excursion PSD
2017 Ford F450